Product Name:

Thiophene

Synonyms:

Furan, Thio-;

CAS:

110-02-1

MF:

C4H4S

MW:

84.14

EINECS:

203-729-4

Product Categories:

Thiophenes;BuildingBlocks;Thiophene;C4 to C6;Chemical Synthesis;Heterocyclic Building Blocks

Melting point 

-38 °C

Boiling point 

84 °C(lit.)

density 

1.051 g/mL at 25 °C(lit.)

vapor density 

2.9 (vs air)

vapor pressure 

40 mm Hg ( 12.5 °C)

refractive index 

n20/D 1.529(lit.)

Fp 

-9 °C

Storage temp. 

Flammables area

Water Solubility 

INSOLUBLE

Stability:

Stable. Highly flammable. Incompatible with strong oxidizing agents, nitrates.

CAS Data Base Reference

110-02-1(CAS DataBase Reference)

Hazard Codes 

F,Xn,Xi,T

Risk Statements 

45-46-11-20/21/22-41-52/53-36-20/22-37/38-22-48/20/21/22

Safety Statements 

53-26-39-45-61-36/37/39-16-36

RIDADR 

UN 2414 3/PG 2

WGK Germany 

3

RTECS 

XM7350000

Hazard Note 

Irritant/Highly Flammable

HazardClass 

3

PackingGroup 

II

HS Code 

29349990

Hazardous Substances Data

110-02-1(Hazardous Substances Data)

Chemical Properties

It is colorless, transparent liquid with an aromatic odor similar to benzene. It is soluble in alcohol, ether and other organic solvents but insoluble in water.

Uses

1. It is used not only for the synthesis of cephalosporin drugs, but also for the production of dyes, synthetic resins, solvents, etc. 
2. It is used for making drugs and plasticizers; thiophene is an important organic chemical raw material which has broad range of applications. It is mainly used for dyes, medicines and resins. It can be used for synthesis of new broad-spectrum cephalosporin antibiotic, and is an important pharmaceutical and chemical additive. It can also be applied for the manufacture of color films and trick photography and synthesizing a complicated reagent used for the extraction and separation of uranium and other metals.
3. It is used as the raw material and a plasticizer of medicine, dyes, and plastics.
4. It is mainly used as the intermediates of pharmaceutical industry used for preparing thiophene acetic pyridine, and pyrantel. It can also been used as a raw material for synthesizing resin and dye industry. It is also be used as an organic solvent. As a chemical reagent, it is used as a standard reagent for chromatography analysis.
5. It is used as a solvent, standard reference agent for chromatography analysis, and also for organic synthesis.
6. Thiophene can be used for the manufacture of dyes, pharmaceuticals and resin; used for the synthesis of new broad-spectrum cephalosporin antibiotics; used for the manufacture of color films and trick photography; used for the synthesis of some complex reagent; it is an important intermediate in the synthesis of Bakelite and resins. Thiophene itself is a good dewaxing solvents and paint cleaners. The derivatives of thiophene have a variety of pharmacological activities. There are a variety of thiophene-azo dyes with excellent performance. The sulfonylurea derivatives of thiophene are new herbicides of ultra-efficient as well as low toxicity. Other derivatives can also be used as insecticides, fungicides, and animal and plant growth-promoting agent. In addition, some derivatives of thiophene are also the component of organic semiconductors. In short, thiophene and its derivatives have a very important position in the pharmaceutical industry, dye industry, pesticide industry, resin industry, and chemical industry.