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Keywords
- 4-Amino-3-(p-chlorophenyl)butyric acid
- Baclofen
- CAS No.1134-47-0
Quick Details
- ProName: Baclofen
- CasNo: 1134-47-0
- Molecular Formula: C10H12ClNO2
- Appearance: odorless white to off-white crystallin...
- Application: skeletal muscle relaxants and sedative...
- DeliveryTime: 5-7 days after receiving payment
- PackAge: aluminum foil packing or Fiber Can
- Port: Qingdao/Shanghai/Tianjin/Ningbo
- ProductionCapacity: 3 Metric Ton/Month
- Purity: min 99%
- Storage: keep it at cool dry ventilated place
- Transportation: UN 2811 6.1/PG 3 Hazard Class 6.1(b) ...
- LimitNum: 50 Gram
Superiority
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Details
Product Name: Baclofen CAS No.: 1134-47-0
MF: C10H12ClNO2 EINECS No.: 214-486-9
Place of Origin:China (Mainland) Type: Baclofen
Brand Name:KRCHEM Model :API
Purity: 99%
Appearance: Odorless or practically odorless white to off-white crystalline powder.
Shelf life: 2 Years
Packing: Drum, Plastic Container
Usage:Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord. Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s. Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury. In addition, the intrathecal injection therapy of the product in clinical application can further improve the clinical efficacy, and make it possible to adjust drugs dosage which stabilizes the treatment effect. For the past 10 years, the clinical application of central muscle relaxant baclofen has made significant progress, particularly in accumulating a lot of experiences in the neurological rehabilitation treatment of reducing muscular tension and pain alleviation treatment.
Description
High quality baclofen
Apperance: white powder
CAS 1134-47-0
Quality:USP standard
packing:25kgs/drum
Introduction
Baclofen is one kind of white powder or white to very faintly yellow solid. The IUPAC Name of this chemical is 4-Amino-3-(4-chlorophenyl)butanoic acid. Its Classification Code is Central Nervous System Agents .
Usage
Baclofen can be used as Specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.
COA
Items | Specifications | Results |
Appearance | white crystalline hygroscopic powder | Conform |
Identification | IR in accordance with USP RS | Conform |
Specific optical Rotation [α] | -29.0°∼-32° | -31.4° |
pH | 5.5-9.5 | 7.2 |
Moisture content | ≤4% | 0.25% |
Residue on ignition | ≤0.5% | 0.03% |
Chloride | ≤0.4% |
<0.4% |
Heavy metals | <0.01% | <0.001 |
Limit of potassium | ≤0.2% | 0.00% |
Limit of Sodium | ≤0.1% | 0.01% |
Assay | 97.0% ∼103.0% | 99.4% |
Residue solvents(ethanol) | ≤0.5% | 0.07% |
Cyanide | Not be detected | N.D. |
Conclusion | The results complies with USP36. |