Zibo Kunran Enterprises Co. LTD

Zibo Kunran Enterprises Co. LTD
Country:  China (Mainland)
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Ms.Mona Zhang
Tel: 0086 533 5200669
Ms.Mona Zhang
Tel: 865335200669
Ms.Minerva
Tel: 86 533 5200669
Fax:  0086 533 5207669
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Diludine

Diludine CAS NO.1149-23-1

  • Product Details

Keywords

  • DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE
  • 3,5-BIS(CARBOETHOXY)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE
  • 2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER

Quick Details

  • ProName: Diludine
  • CasNo: 1149-23-1
  • Molecular Formula: C13H19NO4
  • Appearance: light yellow powder or needle crystal
  • Application: feed additive, Growth promoter
  • DeliveryTime: c.a 10 days depending on QTY
  • PackAge: 25KG/Carton or negotiable
  • Port: Qingdao/Shanghai/Tianjin/Ningbo
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 98%-102%
  • Storage: Keep away from light and air in dry wa...
  • Transportation: By Sea, Air, Express
  • LimitNum: 1 Metric Ton
  • Valid Period: 2 Years
  • Heavy Metal: max 10ppm

Superiority

Growth promoter

Antioxidation

Regulate secretion, enhance Serum Thyroid Hormone (T3)level

Improve immunity

Promote digestive absorption

Details

Product Name:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Synonyms:

DILUDINE;DIETHYL 2,6-DIMETHYL-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE;
DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE;
DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE;
AURORA 4780;3,5-DICARBETHOXY-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE;
3,5-BIS(CARBOETHOXY)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE;
2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER

CAS:

1149-23-1

MF:

C13H19NO4

MW:

253.29

EINECS:

214-561-6

Product Categories:

Pharmaceutical Intermediates;Pyridines, Pyrimidines, Purines and Pteredines;C9 to C46;Heterocyclic Building Blocks;Pyridines;C9 to C46;Heterocyclic Building Blocks;fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, pharmaceutical intermediates;Building Blocks;C13 to C15;Chemical Synthesis;Heterocycle-Pyridine series

Appearance: light yellow powder or needle crystal

M.P.: 176℃-183℃

Assay: 98%-102%

Loss on drying: ≤0.5%

Residue: ≤0.5%

Heavy metal:≤ 10 ppm

Packing: 25 KG/Carton

Storage:Keep away from light and air in dry warehouse, for two years

 

Name

Diludine

EINECS 214-561-6
CAS No. 1149-23-1 Density 1.104 g/cm3
Solubility   Melting Point 176-183 °C
Formula C13H19NO4 Boiling Point 351.8 °C at 760 mmHg
Molecular Weight 253.30 Flash Point 166.6 °C
Transport Information   Appearance white power
Safety 26 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 1149-23-1 (Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate) Hazard Symbols IrritantXi
Synonyms

3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-, diethyl ester (6CI,7CI,8CI,9CI);2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester;2,6-Dimethyl-3,5-di(carboethoxy)-1,4-dihydropyridine;2,6-Dimethyl-3,5-dicarbethoxy-1,4-dihydropyridine;2,6-Dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine;3,5-Bis(ethoxycarbonyl)-1,4-dihydro-2,6-dimethylpyridine;Diethyl2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Etidin;

   

Diludine Specification

The Diludine with CAS registry number of 1149-23-1 is also known as Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate. The IUPAC name is Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. It belongs to product categories of Pharmaceutical Intermediates; Pyridines, Pyrimidines, Purines and Pteredines; C9 to C46; Heterocyclic Building Blocks; Pyridines;C9 to C46; Heterocyclic Building Blocks; Fine Chemicals, Specialty Chemicals, Intermediates, Electronic Chemical, Organic Synthesis, Pharmaceutical Intermediates. Its EINECS registry number is 214-561-6. In addition, the formula is C13H19NO4 and the molecular weight is 253.30. This chemical may cause inflammation to the skin or other mucous membranes. What's more, it is used as feed additive.

Physical properties about Diludine are: (1)ACD/LogP: 2.52; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.51; (4)ACD/LogD (pH 7.4): 2.51; (5)ACD/BCF (pH 5.5): 47.55; (6)ACD/BCF (pH 7.4): 48.01; (7)ACD/KOC (pH 5.5): 550.66; (8)ACD/KOC (pH 7.4): 555.99; (9)#H bond acceptors: 5; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 6; (12)Index of Refraction: 1.489; (13)Molar Refractivity: 66.18 cm3; (14)Molar Volume: 229.2 cm3; (15)Surface Tension: 35.7 dyne/cm; (16)Density: 1.104 g/cm3; (17)Flash Point: 166.6 °C; (18)Enthalpy of Vaporization: 59.66 kJ/mol; (19)Boiling Point: 351.8 °C at 760 mmHg; (20)Vapour Pressure: 4.01E-05 mmHg at 25 °C.

Preparation of Diludine: it is prepared by reaction of acetoacetic acid ethyl ester with formaldehyde. The reaction needs reagent NH4HCO3 and solvent H2O with other condition of heating for 30 minutes. The yield is about 86.3%.

Diludine is prepared by reaction of acetoacetic acid ethyl ester with formaldehyde.

Uses of Diludine: it is used to produce 2,6-dimethyl-pyridine-3,5-dicarboxylic acid diethyl ester. The reaction occurs with reagents silica chloride, NaNO2, SiO2/H2O and solvent CH2Cl2 at the temperature of 20 °C for 30 minutes. The yield is about 92%.

Diludine is used to produce 2,6-dimethyl-pyridine-3,5-dicarboxylic acid diethyl ester.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: CCOC(=O)C1=C(NC(=C(C1)C(=O)OCC)C)C
2. InChI: InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3
3. InChIKey: LJXTYJXBORAIHX-UHFFFAOYSA-N

The toxicity data is as follows:

 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 12gm/kg (12000mg/kg)   United States Patent Document. Vol. #4769382,
mouse LD50 intraperitoneal > 30gm/kg (30000mg/kg)   United States Patent Document. Vol. #4769382,
mouse LD50 oral > 32gm/kg (32000mg/kg)   U.S.S.R. Patent Document. Vol. #0546335,
rat LD50 intraperitoneal > 16gm/kg (16000mg/kg)   United States Patent Document. Vol. #4769382,

 

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