1. Factory steady offer directly;

2. More than 5 years of production and process improved experience;

3. Professional hazard chemical Logistics;

4. Reliable quality assurance

5. Punctual delivery time

Thiosalicylic acid in hot sale with competitive price

Thiosalicylic acid is an organosulfur compound containing carboxyl and sulfhydryl functional groups. Its molecular formula is C₆H₄(SH)(CO₂H). it is a yellow solid that is slightly soluble in water, ethanol and diethyl ether, and alkanes, but more soluble in DMSO.

Preparation and uses

Thiosalicylic acid is prepared from 2-aminobenzoic acid via diazotization.

Thiosalicylic acid is a precursor to the dyestuff thioindigo. Thiosalicylic acid is also used to make the vaccine preservative thiomersal.

Other aspects

It is a precursor to drug candidates for treatment of atherosclerosis and melanoma.

Product Name: Thiosalicylic acid

Synonyms: 2-Carboxythiophenol; 2-mercapto-benzoic acid; 
2-Sulfanylbenzoic acid; 2-thio-salicylicaci; 
Benzoic acid, o-mercapto-; o-Benzoic acid thiol;
o-benzoicacidthiol; o-Carboxythiophenol

CAS: 147-93-3     EINECS: 205-704-3

MF: C7H6O2S    MW: 154.19

Thiosalicylic acid Chemical Properties

Melting point  162-165 °C(lit.)

Boiling point  247.55°C (rough estimate)

density  1.49

refractive index  1.5100 (estimate)

Fp  150 °C

Storage temp.  0-6°C

Form  Fine Crystalline Powder

Color  White to yellow

Water Solubility  soluble in hot water

Sensitive  Air & Light Sensitive

CAS DataBase Reference 147-93-3(CAS DataBase Reference)

Safety Information

Hazard Codes   Xi,Xn,N

Risk Statements   36/37/38-20/21/22

Safety Statements   26-36/37/39-36

TSCA   Yes

HS Code   29309070

Hazardous Substances Data 147-93-3(Hazardous Substances Data)

Thiosalicylic acid Usage And Synthesis

Chemical Properties white to light yellow crystal powder

Uses
1. Trapping agent used in the desulfenylation of 3-indolyl sulfides.1 Condenses with diamines to form macrocyclic diamides.2

2. Used as trapping agent in the desulfenylation of 3-indolyl sulfides;Used to condense with diamines to form macrocyclic diamides.

3. A trapping agent used in the desulfenylation of 3-indolyl sulfides

Definition: A sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid.

Purification Methods
Crystallise the thio acid from hot EtOH (4mL/g), after adding hot distilled water (8mL/g) and boiling with charcoal. The hot solution is filtered, cooled, the solid is collected and dried in vacuo (P2O5). Crystallise it from AcOH and sublime in vacuo.