Product Name:

Chloroacetyl chloride

Synonyms:

Acetylchloride,chloro-;alpha-Chloroacetyl chloride;CH2ClCOCl;
chloracetyl; chloruredechloracetyle;monochloroacetylchloridc;
MONO CHLORO ACETYL CHLORIDE

CAS:

79-04-9

MF:

C2H2Cl2O

MW:

112.94

EINECS:

201-171-6

Product Categories:

Pharmaceutical Intermediates;Halogen compounds;
Organics;Acid Halides;Carbonyl Compounds;
Organic Building Blocks;Acid Halides;Building Blocks;
Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;
API Intermediate;synthesis of pesticides, herbicides

Mol File:

79-04-9.mol

Chloroacetyl chloride Chemical Properties

Melting point 

−22 °C(lit.)

Boiling point 

105-106 °C(lit.)

density 

1.419 g/mL at 20 °C

vapor density 

3.9 (vs air)

vapor pressure 

60 mm Hg ( 41.5 °C)

refractive index 

n20/D 1.453(lit.)

Fp 

>100°C

storage temp. 

Store at RT.

solubility 

Miscible with ethyl ether, acetone, benzene and carbon tetrachloride.

form 

Liquid

color 

Clear colorless to slightly yellow

Water Solubility 

reacts

FreezingPoint 

-22.5℃

Sensitive 

Moisture Sensitive

Stability:

Stable. Incompatible with strong bases, alcohols, strong oxidizing agents. May react violently on exposure to water or moisture.

CAS Data Base Reference

79-04-9(CAS DataBase Reference)

NIST Chemistry Reference

Acetyl chloride, chloro-(79-04-9)

EPA Substance Registry System

Chloroacetyl chloride (79-04-9)

Safety Information

Hazard Codes 

T,C,N

Risk Statements 

14-23/24/25-35-48/23-50-29

Safety Statements 

9-26-36/37/39-45-61-7/8

RIDADR 

UN 1752 6.1/PG 1

WGK Germany 

3

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

I

HS Code 

29159000

Hazardous Substances Data

79-04-9(Hazardous Substances Data)

Chloroacetyl chloride Usage And Synthesis

Chemical Properties

Clear colorless liquid

Chemical Properties

Chloroacetyl chloride is a colorless to yellowish liquid with a very pungent, extremely irritating, odor.

Uses

In the synthesis of organic compounds.

Definition

A lachrymator.

General Description

A colorless to light yellow liquid with a very pungent odor. Very toxic by inhalation. Corrosive to metals and tissue.

Reactivity Profile

Chloroacetyl chloride reacts rapidly with water. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts.

Hazard

Irritant to eyes, corrosive to skin. Upper respiratory tract irritant.

Health Hazard

Inhalation causes severe irritation of upper respiratory system. External contact causes severe irritation of eyes and skin. Ingestion causes severe irritation of mouth and stomach.

Safety Profile

Poison by ingestion and intravenous routes. Mildly toxic by inhalation. Corrosive. A lachrymator. When heated to decomposition it emits toxic fumes of Cl-.

Potential Exposure

Highly toxic by inhalation. Chloroacetyl chloride is used in the manufacture of acetophenone. It is used in the manufacture of a number of pesticides including: alachlor, allidochlor, butachlor, dimethachlor, formothion, mecarbam, metolachlor, propachlor. It is also used in the manufacture of pharmaceuticals, such as chlordiazepoxide hydrochloride, diazepam, lidocaine, mianserin.

Shipping

UN1752 Chloroacetyl chloride, Hazard class: 6.1;
 Labels: 6.1-Poison Inhalation Hazard, 8-Corrosive material,
Inhalation Hazard Zone B.

Incompatibilities

Reacts violently with water, steamforming chloroacetic acid and hydrogen chloride gas. Reacts with alcohols, powdered metals; sodium amide; combustibles; and many organics, causing toxic fumes, fire, and explosion hazard. On contact with air it emits corrosive gas. Decomposes when heated forming phosgene gas. Corrosive to metals.

Waste Disposal

It may be discharged into sodium bicarbonate solution, then flushed to the sewer with water.